Source:http://linkedlifedata.com/resource/pubmed/id/17697810
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
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| pubmed:dateCreated |
2007-8-16
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| pubmed:abstractText |
There are limited data regarding the prognostic value of QRS complex fragmentation, defined as changes in QRS morphology (<120 ms) with different RSR' patterns: additional R waves, notched S wave, or >1 R' wave. The purpose of our analysis was to assess the prognostic value of presence of Q waves and QRS fragmentation for predicting recurrent cardiac events, defined as cardiac death, nonfatal myocardial infarction (MI), or unstable angina, whichever occurs first, in 350 patients with first Q-wave MI. In follow-up (2 months on average) electrocardiograms (ECGs), 277 patients (79%) had persistent Q waves and 73 (21%) had resolution of Q waves. Independently of Q waves, presence of QRS complex fragmentation was found in 187 patients (53%). Resolved Q waves on 2-month ECGs was associated with worsened prognosis (adjusted hazard ratio [HR] 2.33, p = 0.007), whereas presence of any fragmented QRS did not increase risk of recurrent cardiac events (adjusted HR 0.93, p = 0.79). Among patients for whom Q waves disappeared on 2-month ECGs, patients with QRS fragmentation (n = 37) had over twofold higher risk of recurrent events (adjusted HR 2.68, p = 0.004) compared with those without fragmented QRS and persistent Q waves. In conclusion, presence of fragmented QRS independently of Q waves was not associated with increased risk of recurrent events in the general population of patients after MI. However, among patients with resolved Q waves, fragmented QRS was associated with increased risk of cardiac events. Fragmented QRS complex should not be neglected in patients with transient Q waves after myocardial infarction.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
0002-9149
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
15
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| pubmed:volume |
100
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
583-6
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| pubmed:meshHeading |
pubmed-meshheading:17697810-Canada,
pubmed-meshheading:17697810-Confidence Intervals,
pubmed-meshheading:17697810-Disease Progression,
pubmed-meshheading:17697810-Electrocardiography,
pubmed-meshheading:17697810-Female,
pubmed-meshheading:17697810-Follow-Up Studies,
pubmed-meshheading:17697810-Humans,
pubmed-meshheading:17697810-Israel,
pubmed-meshheading:17697810-Male,
pubmed-meshheading:17697810-Middle Aged,
pubmed-meshheading:17697810-Myocardial Infarction,
pubmed-meshheading:17697810-Prognosis,
pubmed-meshheading:17697810-Recurrence,
pubmed-meshheading:17697810-Retrospective Studies,
pubmed-meshheading:17697810-Risk Factors,
pubmed-meshheading:17697810-Severity of Illness Index,
pubmed-meshheading:17697810-Time Factors,
pubmed-meshheading:17697810-United States
|
| pubmed:year |
2007
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| pubmed:articleTitle |
Prognostic significance of fragmented QRS complex for predicting the risk of recurrent cardiac events in patients with Q-wave myocardial infarction.
|
| pubmed:affiliation |
Heart Research Follow-up Program, Cardiology Division, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA.
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| pubmed:publicationType |
Journal Article,
Multicenter Study
|