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pubmed:abstractText |
Loopin-1 is an abundant, male germ line specific protein of Drosophila melanogaster. The polyclonal antibody T53-F1 specifically recognizes Loopin-1 and enables its visualization on the Y-chromosome lampbrush-like loop named kl-3 during primary spermatocyte development, as well as on sperm tails. In order to test lampbrush-like loop evolutionary conservation, extensive phase-contrast microscopy and immunostaining with T53-F1 antibody was performed in other drosophilids scattered along their genealogical tree.
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pubmed:affiliation |
Dipartimento di Genetica e Biologia Molecolare, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy. roberto.piergentili@uniroma1.it
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