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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-8-16
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pubmed:abstractText |
The incidence of gallbladder cancer (GBC) is usually paralleled by the prevalence of gallstone disease, and genes of cholesterol metabolism have been implicated in gallstone disease. The XbaI and insertion/deletion (ins/del) polymorphism of Apolipoprotein B (APOB) appears to influence cholesterol homoeostasis and possibly risk for gallstone disease. We examined the effect of these polymorphisms individually as well as their haplotypes on GBC and gallstone patients in North Indian population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1478-3223
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1008-15
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pubmed:meshHeading |
pubmed-meshheading:17696941-Adult,
pubmed-meshheading:17696941-Apolipoproteins B,
pubmed-meshheading:17696941-Case-Control Studies,
pubmed-meshheading:17696941-Female,
pubmed-meshheading:17696941-Gallbladder Neoplasms,
pubmed-meshheading:17696941-Gallstones,
pubmed-meshheading:17696941-Gene Deletion,
pubmed-meshheading:17696941-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17696941-Gene Frequency,
pubmed-meshheading:17696941-Genetic Predisposition to Disease,
pubmed-meshheading:17696941-Haplotypes,
pubmed-meshheading:17696941-Humans,
pubmed-meshheading:17696941-Male,
pubmed-meshheading:17696941-Middle Aged,
pubmed-meshheading:17696941-Odds Ratio,
pubmed-meshheading:17696941-Polymorphism, Genetic,
pubmed-meshheading:17696941-Protein Sorting Signals,
pubmed-meshheading:17696941-Risk Assessment,
pubmed-meshheading:17696941-Risk Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Haplotype analysis of signal peptide (insertion/deletion) and XbaI polymorphisms of the APOB gene in gallbladder cancer.
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pubmed:affiliation |
Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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