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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-7
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pubmed:abstractText |
DLG5 p.R30Q has been reported to be associated with Crohn disease (CD), but this association has not been replicated in most studies. A recent analysis of gender-stratified data from two case-control studies and two population cohorts found an association of DLG5 30Q with increased risk of CD in men but not in women and found differences between 30Q population frequencies for males and females. Male-female differences in population allele frequencies and male-specific risk could explain the difficulty in replicating the association with CD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1468-6244
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pubmed:author |
pubmed-author:AnneseVV,
pubmed-author:BüningCC,
pubmed-author:BarclayM LML,
pubmed-author:BinghamS ASA,
pubmed-author:BrandSS,
pubmed-author:BrowningB LBL,
pubmed-author:CastroMM,
pubmed-author:CucchiaraSS,
pubmed-author:DallapiccolaBB,
pubmed-author:DrummondHH,
pubmed-author:FergusonL RLR,
pubmed-author:FerrarisAA,
pubmed-author:FisherS ASA,
pubmed-author:GearryR BRB,
pubmed-author:GlazCC,
pubmed-author:HenckaertsLL,
pubmed-author:HuebnerCC,
pubmed-author:KnafelzDD,
pubmed-author:LakatosLL,
pubmed-author:LakatosP LPL,
pubmed-author:LatianoAA,
pubmed-author:LimPP,
pubmed-author:Müller-MyhsokBB,
pubmed-author:MatherLL,
pubmed-author:NewmanW GWG,
pubmed-author:NimmoE RER,
pubmed-author:NobleC LCL,
pubmed-author:PalmieriOO,
pubmed-author:ParkerBB,
pubmed-author:PetermannII,
pubmed-author:RutgeertsPP,
pubmed-author:SatsangiJJ,
pubmed-author:ShellingA NAN,
pubmed-author:SiminovitchK AKA,
pubmed-author:TörökH-PHP,
pubmed-author:TremellingMM,
pubmed-author:ValvanoM RMR,
pubmed-author:VermeireSS,
pubmed-author:WittHH
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-42
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pubmed:meshHeading |
pubmed-meshheading:17693570-Alleles,
pubmed-meshheading:17693570-Case-Control Studies,
pubmed-meshheading:17693570-Crohn Disease,
pubmed-meshheading:17693570-European Continental Ancestry Group,
pubmed-meshheading:17693570-Female,
pubmed-meshheading:17693570-Gene Frequency,
pubmed-meshheading:17693570-Genetic Predisposition to Disease,
pubmed-meshheading:17693570-Genotype,
pubmed-meshheading:17693570-Humans,
pubmed-meshheading:17693570-Male,
pubmed-meshheading:17693570-Membrane Proteins,
pubmed-meshheading:17693570-Odds Ratio,
pubmed-meshheading:17693570-Sex Factors,
pubmed-meshheading:17693570-Tumor Suppressor Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts.
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pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
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