Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2007-10-10
pubmed:abstractText
Invasive pneumococcal disease (IPD) is 3-5 times more common among Navajo adults than in the general US population. The authors conducted a case-control study to identify risk factors for IPD among Navajo adults. Navajos aged > or =18 years with IPD were identified through prospective, population-based active laboratory surveillance (December 1999-February 2002). Controls matched to cases on age, gender, and neighborhood were selected. Risk factors were identified through structured interviews and medical record reviews. The authors conducted a matched analysis based on 118 cases and 353 controls. Risk factors included in the final multivariable analysis were chronic renal failure (odds ratio (OR) = 2.6, 95% confidence interval (CI): 0.9, 7.7), congestive heart failure (OR = 5.6, 95% CI: 2.2, 14.5), self-reported alcohol use or alcoholism (OR = 2.9, 95% CI: 1.5, 5.4), body mass index (weight (kg)/height (m)(2)) <5th (OR = 3.2, 95% CI: 1.0, 10.6) or >95th (OR = 2.8, 95% CI: 1.0, 8.0) percentile, and unemployment (OR = 2.6, 95% CI: 1.2, 5.5). The population attributable fractions were 10% for chronic renal failure, 18% for congestive heart failure, 30% for self-reported alcohol use or alcoholism, 6% for body mass index, and 20% for unemployment. Several modifiable risk factors for IPD in Navajos were identified. The high prevalence of renal failure, alcoholism, and unemployment among Navajo adults compared with the general US population may explain some of their increased risk of IPD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0002-9262
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
166
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1080-7
pubmed:meshHeading
pubmed-meshheading:17693393-Adolescent, pubmed-meshheading:17693393-Adult, pubmed-meshheading:17693393-Aged, pubmed-meshheading:17693393-Alcoholism, pubmed-meshheading:17693393-Analysis of Variance, pubmed-meshheading:17693393-Body Mass Index, pubmed-meshheading:17693393-Case-Control Studies, pubmed-meshheading:17693393-Female, pubmed-meshheading:17693393-Heart Failure, pubmed-meshheading:17693393-Humans, pubmed-meshheading:17693393-Indians, North American, pubmed-meshheading:17693393-Kidney Failure, Chronic, pubmed-meshheading:17693393-Male, pubmed-meshheading:17693393-Middle Aged, pubmed-meshheading:17693393-Multivariate Analysis, pubmed-meshheading:17693393-Pneumococcal Infections, pubmed-meshheading:17693393-Population Surveillance, pubmed-meshheading:17693393-Prospective Studies, pubmed-meshheading:17693393-Questionnaires, pubmed-meshheading:17693393-Risk Factors, pubmed-meshheading:17693393-Socioeconomic Factors, pubmed-meshheading:17693393-Streptococcus pneumoniae, pubmed-meshheading:17693393-United States
pubmed:year
2007
pubmed:articleTitle
Risk factors for invasive pneumococcal disease among Navajo adults.
pubmed:affiliation
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. jwatt@jhsph.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't