Linked Life Data

17693024

Source:http://linkedlifedata.com/resource/pubmed/id/17693024

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2007-9-17
pubmed:abstractText
We investigated the mechanisms underlying severe bleeding occurring upon consumption of Ferula communis. The prenylated coumarin ferulenol extracted from this plant did not directly affect blood coagulation but showed hepatocyte cytotoxicity and, at non-cytotoxic concentrations (<100 nM), impaired factor X biosynthesis (40% reduction). Studies with ferulenol derivatives indicated the prenyl residue as major determinant of ferulenol activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:volume
1770
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1437-40
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Characterization of anti-coagulant properties of prenylated coumarin ferulenol.
pubmed:affiliation
Dipartimento di Biochimica e Biologia Molecolare, Università di Ferrara, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't