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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-9-26
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pubmed:abstractText |
Spontaneous cervical artery dissection (sCAD) is a common cause of stroke in patients below 55 years. Dermal connective tissue abnormalities have been observed in up to 60% of patients. A chromosomal locus for connective tissue abnormalities associated with sCAD has been mapped to chromosome 15q24 to a candidate region containing the lysyl oxidase-like 1 gene (LOXL1). LOXL1 an excellent candidate susceptibility gene for non-familial sCAD was investigated by mutation analysis and a genetic association study.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1015-9770
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-8
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pubmed:meshHeading |
pubmed-meshheading:17690546-Adult,
pubmed-meshheading:17690546-Amino Acid Oxidoreductases,
pubmed-meshheading:17690546-Aneurysm, Dissecting,
pubmed-meshheading:17690546-Cervical Vertebrae,
pubmed-meshheading:17690546-DNA Mutational Analysis,
pubmed-meshheading:17690546-Exons,
pubmed-meshheading:17690546-Female,
pubmed-meshheading:17690546-Gene Frequency,
pubmed-meshheading:17690546-Genetic Predisposition to Disease,
pubmed-meshheading:17690546-Humans,
pubmed-meshheading:17690546-Introns,
pubmed-meshheading:17690546-Linkage Disequilibrium,
pubmed-meshheading:17690546-Male,
pubmed-meshheading:17690546-Middle Aged,
pubmed-meshheading:17690546-Models, Genetic,
pubmed-meshheading:17690546-Odds Ratio,
pubmed-meshheading:17690546-Polymorphism, Single Nucleotide,
pubmed-meshheading:17690546-Retrospective Studies,
pubmed-meshheading:17690546-Risk Assessment,
pubmed-meshheading:17690546-Risk Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Association between single nucleotide polymorphisms in the lysyl oxidase-like 1 gene and spontaneous cervical artery dissection.
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pubmed:affiliation |
Leibniz Institute of Atherosclerosis Research, University of Münster, Münster, Germany. gkuhlen@uni-muenster.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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