Linked Life Data

17688277

Source:http://linkedlifedata.com/resource/pubmed/id/17688277

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-4-2
pubmed:abstractText
Staphylococcus aureus is a common infecting agent of many surgical sites. As a commensal organism to humans and rabbits, the infection process may occur due to native or exogenous S. aureus. We applied exogenous S. aureus ATCC 49230 once weekly to the surgical site of an osseointegrated pin in 20 New Zealand white rabbits. Clinical signs of infection resulted in euthanasia and at necropsy samples were collected from putatively infected sites. The predominant organism cultured was S. aureus. We observed various beta-hemolysis patterns of S. aureus on culture media and used pulsed field gel electrophoresis (PFGE) to determine whether there were distinct strains of S. aureus collected from various sites of the rabbits. On the basis of PFGE results, we found that the exogenous S. aureus ATCC 49230 was not the S. aureus cultured during necropsy, but that S. aureus native to the rabbits was in fact the infecting agent. We conclude that this rabbit model for S. aureus infection, which has not been described previously, may contribute to understanding the pathogenesis of S. aureus infections in future studies with simulated osseointegrated pin infections secondary to S. aureus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1552-4965
pubmed:author
pubmed:copyrightInfo
Copyright 2007 Wiley Periodicals, Inc.
pubmed:issnType
Electronic
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
366-70
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Characterization of Staphylococcus aureus strains in a rabbit model of osseointegrated pin infections.
pubmed:affiliation
Associated Regional and University Pathologists Laboratories, ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA. dustin.williams@aruplab.com
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.