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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1992-2-25
|
| pubmed:abstractText |
Reserpine pre-treatment causes a considerable decrease in typical red-orange doxorubicin fluorescence of the organs examined (kidney, large intestine, spleen) and a similar picture is observed after calcium antagonists administration. This effect is far more evident in the spleen and large intestine than in the kidney; moreover, it seems more marked in young rats compared with aged ones. An inhibitory action of these drugs on the anthracycline transport carrier through the cell membrane is hypothesized.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0258-851X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
171-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1768787-Aging,
pubmed-meshheading:1768787-Animals,
pubmed-meshheading:1768787-Doxorubicin,
pubmed-meshheading:1768787-Intestine, Large,
pubmed-meshheading:1768787-Kidney,
pubmed-meshheading:1768787-Male,
pubmed-meshheading:1768787-Microscopy, Fluorescence,
pubmed-meshheading:1768787-Muscle, Smooth,
pubmed-meshheading:1768787-Muscle Development,
pubmed-meshheading:1768787-Nicardipine,
pubmed-meshheading:1768787-Organ Specificity,
pubmed-meshheading:1768787-Rats,
pubmed-meshheading:1768787-Rats, Inbred Strains,
pubmed-meshheading:1768787-Reserpine,
pubmed-meshheading:1768787-Spleen,
pubmed-meshheading:1768787-Verapamil
|
| pubmed:articleTitle |
Effect of reserpine and calcium antagonists on doxorubicin storage in various organs of young and senescent rats.
|
| pubmed:affiliation |
Istituto di Anatomia Umana Normale, Facoltà di Medicina e Chirurgia, Università degli Studi di Pisa, Italia.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|