Source:http://linkedlifedata.com/resource/pubmed/id/17687556
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-1-9
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pubmed:abstractText |
Secondary amyloidosis (AA amyloidosis) has rarely been described in patients with systemic lupus erythematosus (SLE). We, herein, present a 56-year-old female patient, who developed AA amyloidosis following a 22-year history of SLE. She developed severe mitral regurgitation complicated with chordae tendinea rupture that led to acute congestive heart failure and went on a mitral valve replacement, where no flare symptoms of SLE were present. Three months after the operation, she presented with a nephrotic-range proteinuria, acute renal failure, and severe sepsis. She was found to have new vegetations on replaced valve and multi-organ failure caused her death. Re-evaluation of the excised mitral valve revealed AA amyloid deposition. Post-mortem biopsies from the kidney and bone marrow also revealed secondary amyloidosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0172-8172
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
367-70
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17687556-Acute Kidney Injury,
pubmed-meshheading:17687556-Amyloidosis,
pubmed-meshheading:17687556-Chordae Tendineae,
pubmed-meshheading:17687556-Fatal Outcome,
pubmed-meshheading:17687556-Female,
pubmed-meshheading:17687556-Heart Failure,
pubmed-meshheading:17687556-Heart Rupture,
pubmed-meshheading:17687556-Heart Valve Prosthesis Implantation,
pubmed-meshheading:17687556-Humans,
pubmed-meshheading:17687556-Lupus Erythematosus, Systemic,
pubmed-meshheading:17687556-Middle Aged,
pubmed-meshheading:17687556-Mitral Valve Insufficiency,
pubmed-meshheading:17687556-Multiple Organ Failure,
pubmed-meshheading:17687556-Nephrotic Syndrome,
pubmed-meshheading:17687556-Shock, Septic
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pubmed:year |
2008
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pubmed:articleTitle |
AA amyloidosis associated with systemic lupus erythematosus: impact on clinical course and outcome.
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pubmed:affiliation |
Department of Nephrology, Ankara University School of Medicine, Ibni Sina Hospital, Ankara, 06100, Turkey.
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pubmed:publicationType |
Journal Article,
Case Reports
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