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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1992-2-25
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pubmed:abstractText |
Single guinea-pig ventricular myocytes were loaded with the fluorescent Ca2+ indicator Indo-1 AM and stretched by carbon fibres. Stretching increased resting tension. Sarcomere lengths were increased by 2-18%. It was observed that a stretch increased resting [Ca2+]i in seven out of eight cells. The change in [Ca2+]i increased with the size of the stretch and returned to pre-stretch levels on return to resting cell length. These observations suggest a means by which changes in resting muscle length can modify the contractile state of cardiac muscle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0958-0670
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
975-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1768419-Animals,
pubmed-meshheading:1768419-Calcium,
pubmed-meshheading:1768419-Cytosol,
pubmed-meshheading:1768419-Fluorescence,
pubmed-meshheading:1768419-Guinea Pigs,
pubmed-meshheading:1768419-Indoles,
pubmed-meshheading:1768419-Myocardial Contraction,
pubmed-meshheading:1768419-Myocardium,
pubmed-meshheading:1768419-Sarcomeres
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pubmed:year |
1991
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pubmed:articleTitle |
Stretch-induced increase of resting intracellular calcium concentration in single guinea-pig ventricular myocytes.
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pubmed:affiliation |
Laboratoire d'Electrophysiologie et de Pharmacologie cellulaires, Université de Tours, Faculté des Sciences, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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