Source:http://linkedlifedata.com/resource/pubmed/id/17681731
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-4-8
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pubmed:abstractText |
Mitral regurgitation (MR) in dilated cardiomyopathy (DCM-MR) and MR in ischemic cardiomyopathy (ISC-MR) usually occurs as a result of mitral annulus (MA) dilatation and papillary muscle displacement secondary to global left ventricle remodelling. We propose a method to determine MA area and motion throughout the cardiac cycle and to define papillary muscle position in 3-dimensional space using real-time 3-dimensional echocardiography. Real-time 3-dimensional echocardiography was performed in 24 healthy individuals, and in 30 patients with DCM-MR (n = 15) or ISC-MR (n = 15). Significant intergroup differences were noted in MA surface area (control: 6.4 +/- 1.7 cm(2); DCM-MR: 11.1 +/- 2.6 cm(2); ISC-MR: 9.0 +/- 2.0 cm(2)) and in peak MA motion (control: 8.7 +/- 3.0 mm; DCM-MR: 3.4 +/- 1.7 mm; ISC-MR: 4.9 +/- 1.5 mm). In patients with DCM-MR, papillary muscle symmetry was preserved, whereas in patients with ISC-MR, papillary tethering lengths were unequal as a result of wall-motion abnormalities. Our methodology for dynamic volumetric measurements of the mitral apparatus allows better understanding of MR mechanisms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1097-6795
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-54
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pubmed:meshHeading |
pubmed-meshheading:17681731-Computer Systems,
pubmed-meshheading:17681731-Echocardiography, Three-Dimensional,
pubmed-meshheading:17681731-Female,
pubmed-meshheading:17681731-Humans,
pubmed-meshheading:17681731-Image Interpretation, Computer-Assisted,
pubmed-meshheading:17681731-Male,
pubmed-meshheading:17681731-Middle Aged,
pubmed-meshheading:17681731-Mitral Valve,
pubmed-meshheading:17681731-Mitral Valve Insufficiency,
pubmed-meshheading:17681731-Myocardial Ischemia,
pubmed-meshheading:17681731-Reproducibility of Results,
pubmed-meshheading:17681731-Sensitivity and Specificity
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pubmed:year |
2008
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pubmed:articleTitle |
Quantification of mitral apparatus dynamics in functional and ischemic mitral regurgitation using real-time 3-dimensional echocardiography.
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pubmed:affiliation |
DEIS, University of Bologna, Bologna, Italy.
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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