Source:http://linkedlifedata.com/resource/pubmed/id/17680561
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2007-10-2
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pubmed:abstractText |
The reasons for social inequality in breast cancer survival are far from established. Our study aims to study the importance of a range of socioeconomic factors and comorbid disorders on survival after breast cancer surgery in Denmark where the health care system is tax-funded and uniform. All 25,897 Danish women who underwent protocol-based treatment for breast cancer in 1983-1999 were identified in a clinical database and information on socioeconomic variables and both somatic and psychiatric comorbid disorders was obtained from population-based registries. We used Cox proportional hazards models to estimate the association between socioeconomic position and overall survival and further to analyse breast cancer specific deaths in a competing risk set-up regarding all other causes of death as competing risks. The adjusted hazard ratio (HR) for death was reduced in women with higher education (HR, 0.91; 95% confidence interval (CI), 0.85-0.98), with higher income (HR, 0.93; 95% CI, 0.87-0.98) and with larger dwellings (HR, 0.90; 95% CI, 0.85-0.96 for women living in houses larger than 150 m(2)). Presence of comorbid disorders increased the HR. An interaction between income and comorbid disorders resulting in a 15% lower survival 10 year after primary surgery in poor women with low-risk breast cancer having comorbid conditions ( approximately 65%) compared to rich women with similar breast cancer prognosis and comorbid conditions ( approximately 80%) suggests that part of the explanation for the social inequality in survival after breast cancer surgery in Denmark lies in the access to and/or compliance with management of comorbid conditions in poorer women.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1097-0215
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2007 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
121
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2524-31
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pubmed:meshHeading |
pubmed-meshheading:17680561-Adult,
pubmed-meshheading:17680561-Aged,
pubmed-meshheading:17680561-Breast Neoplasms,
pubmed-meshheading:17680561-Cohort Studies,
pubmed-meshheading:17680561-Comorbidity,
pubmed-meshheading:17680561-Denmark,
pubmed-meshheading:17680561-Female,
pubmed-meshheading:17680561-Health Services Accessibility,
pubmed-meshheading:17680561-Humans,
pubmed-meshheading:17680561-Income,
pubmed-meshheading:17680561-Lymphatic Metastasis,
pubmed-meshheading:17680561-Middle Aged,
pubmed-meshheading:17680561-Odds Ratio,
pubmed-meshheading:17680561-Patient Compliance,
pubmed-meshheading:17680561-Poverty,
pubmed-meshheading:17680561-Proportional Hazards Models,
pubmed-meshheading:17680561-Registries,
pubmed-meshheading:17680561-Socioeconomic Factors,
pubmed-meshheading:17680561-Survival Rate
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pubmed:year |
2007
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pubmed:articleTitle |
Influence of socioeconomic factors on survival after breast cancer--a nationwide cohort study of women diagnosed with breast cancer in Denmark 1983-1999.
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pubmed:affiliation |
Department for Psychosocial Cancer Research, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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