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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-8-7
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pubmed:abstractText |
The morphology of the RPE shows minimal change as the neural retina and choriocapillaris differentiate. Nonetheless, initial studies of proteins related to the outer blood-retinal barrier suggest extensive remodeling of the retinal pigment epithelium (RPE) in response to this changing environment. A genomic approach was used to investigate the extent of this remodeling.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Laminin,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Microtubule-Associated Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Myosins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Subunits,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/lysosomal proteins
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1259-73
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17679949-Actins,
pubmed-meshheading:17679949-Animals,
pubmed-meshheading:17679949-Blood-Retinal Barrier,
pubmed-meshheading:17679949-Cell Cycle Proteins,
pubmed-meshheading:17679949-Chick Embryo,
pubmed-meshheading:17679949-Cluster Analysis,
pubmed-meshheading:17679949-Collagen,
pubmed-meshheading:17679949-Extracellular Matrix,
pubmed-meshheading:17679949-Gene Expression Profiling,
pubmed-meshheading:17679949-Intercellular Junctions,
pubmed-meshheading:17679949-Laminin,
pubmed-meshheading:17679949-Membrane Proteins,
pubmed-meshheading:17679949-Microtubule-Associated Proteins,
pubmed-meshheading:17679949-Myosins,
pubmed-meshheading:17679949-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17679949-Phagocytosis,
pubmed-meshheading:17679949-Pigment Epithelium of Eye,
pubmed-meshheading:17679949-Protein Subunits,
pubmed-meshheading:17679949-Proteins,
pubmed-meshheading:17679949-RNA, Messenger,
pubmed-meshheading:17679949-Receptors, Cell Surface,
pubmed-meshheading:17679949-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17679949-Transcription, Genetic
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pubmed:year |
2007
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pubmed:articleTitle |
Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier.
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pubmed:affiliation |
Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA. lawrence.rizzolo@yale.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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