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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2007-8-7
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pubmed:abstractText |
On proton magnetic resonance spectroscopic imaging ((1)H MRSI), there is a decrease in cerebellar N-acetylaspartate/total creatine (NAA/tCr) in essential tremor (ET), signifying cerebellar neuronal dysfunction or degeneration. Harmane, which is present in the human diet, is a potent tremor-producing neurotoxin. Blood harmane concentrations seem to be elevated in ET.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
7
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
515-20
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17679670-Aspartic Acid,
pubmed-meshheading:17679670-Basal Ganglia,
pubmed-meshheading:17679670-Cerebellar Cortex,
pubmed-meshheading:17679670-Cerebellum,
pubmed-meshheading:17679670-Creatine,
pubmed-meshheading:17679670-Essential Tremor,
pubmed-meshheading:17679670-Female,
pubmed-meshheading:17679670-Harmine,
pubmed-meshheading:17679670-Humans,
pubmed-meshheading:17679670-Lead,
pubmed-meshheading:17679670-Male,
pubmed-meshheading:17679670-Neurotoxins,
pubmed-meshheading:17679670-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:17679670-Pilot Projects,
pubmed-meshheading:17679670-Single-Blind Method,
pubmed-meshheading:17679670-Thalamus,
pubmed-meshheading:17679670-Videotape Recording
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pubmed:year |
2007
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pubmed:articleTitle |
Blood harmane is correlated with cerebellar metabolism in essential tremor: a pilot study.
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pubmed:affiliation |
Gertrude H. Sergievsky Center, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. EDL2@columbia.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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