|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007102,
umls-concept:C0014442,
umls-concept:C0016360,
umls-concept:C0034693,
umls-concept:C0043833,
umls-concept:C0083104,
umls-concept:C0152035,
umls-concept:C0205195,
umls-concept:C0205263,
umls-concept:C1280500,
umls-concept:C1527240,
umls-concept:C1533719
|
|
pubmed:issue |
3-4
|
|
pubmed:dateCreated |
1992-2-14
|
|
pubmed:abstractText |
Juzen-taiho-to (JTT; [Shi-quan-da-bu-tang], a Japanese modified Chinese herbal prescription) in combination with an anticancer drug UFT (5-fluorouracil derivative) prevented the body weight loss and the induction of the colonic cancer in rats treated with a chemical carcinogen 1,2-dimethylhydrazine (DMH), and suppressed markedly the activity of thymidylate synthetase (TS) involved in the de novo pathway of pyrimidine synthesis in colonic cancer induced by DMH.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0192-415X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
233-41
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1767795-Adenocarcinoma,
pubmed-meshheading:1767795-Animals,
pubmed-meshheading:1767795-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1767795-Colonic Neoplasms,
pubmed-meshheading:1767795-Drug Evaluation, Preclinical,
pubmed-meshheading:1767795-Drugs, Chinese Herbal,
pubmed-meshheading:1767795-Fluorouracil,
pubmed-meshheading:1767795-Neoplasm Staging,
pubmed-meshheading:1767795-Rats,
pubmed-meshheading:1767795-Thymidine Kinase,
pubmed-meshheading:1767795-Thymidylate Synthase,
pubmed-meshheading:1767795-Weight Loss
|
|
pubmed:year |
1991
|
|
pubmed:articleTitle |
Anticancer effects of a Chinese herbal medicine, juzen-taiho-to, in combination with or without 5-fluorouracil derivative on DNA-synthesizing enzymes in 1,2-dimethylhydrazine induced colonic cancer in rats.
|
|
pubmed:affiliation |
Medical Research Institute, Tokyo Medical and Dental University, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
