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pubmed-article:17675855pubmed:dateCreated2007-8-6lld:pubmed
pubmed-article:17675855pubmed:abstractTextAlternative splicing represents a source of great diversity for regulating protein expression and function. It has been estimated that one-third to two-thirds of mammalian genes are alternatively spliced. With the sequencing of the chicken genome and analysis of transcripts expressed in chicken tissues, we are now in a position to address evolutionary conservation of alternative splicing events in chicken and mammals. Here, we compare chicken and mammalian transcript sequences of 41 alternatively-spliced genes and 50 frequently accessed genes. Our results support a high frequency of splicing events in chicken, similar to that observed in mammals.lld:pubmed
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pubmed-article:17675855pubmed:authorpubmed-author:GodboutRRlld:pubmed
pubmed-article:17675855pubmed:authorpubmed-author:RohY SYSlld:pubmed
pubmed-article:17675855pubmed:authorpubmed-author:KatyalSSlld:pubmed
pubmed-article:17675855pubmed:copyrightInfoCopyright 2007 S. Karger AG, Basel.lld:pubmed
pubmed-article:17675855pubmed:issnTypeElectroniclld:pubmed
pubmed-article:17675855pubmed:volume117lld:pubmed
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pubmed-article:17675855pubmed:pagination146-57lld:pubmed
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pubmed-article:17675855pubmed:year2007lld:pubmed
pubmed-article:17675855pubmed:articleTitleEvolutionary conservation of alternative splicing in chicken.lld:pubmed
pubmed-article:17675855pubmed:affiliationDepartment of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada.lld:pubmed
pubmed-article:17675855pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17675855pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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