Source:http://linkedlifedata.com/resource/pubmed/id/17675855
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-4
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pubmed:dateCreated |
2007-8-6
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pubmed:abstractText |
Alternative splicing represents a source of great diversity for regulating protein expression and function. It has been estimated that one-third to two-thirds of mammalian genes are alternatively spliced. With the sequencing of the chicken genome and analysis of transcripts expressed in chicken tissues, we are now in a position to address evolutionary conservation of alternative splicing events in chicken and mammals. Here, we compare chicken and mammalian transcript sequences of 41 alternatively-spliced genes and 50 frequently accessed genes. Our results support a high frequency of splicing events in chicken, similar to that observed in mammals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1424-859X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2007 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
146-57
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pubmed:meshHeading |
pubmed-meshheading:17675855-Alternative Splicing,
pubmed-meshheading:17675855-Animals,
pubmed-meshheading:17675855-Brain,
pubmed-meshheading:17675855-Chickens,
pubmed-meshheading:17675855-Evolution, Molecular,
pubmed-meshheading:17675855-Humans,
pubmed-meshheading:17675855-Nerve Tissue Proteins,
pubmed-meshheading:17675855-Organ Specificity,
pubmed-meshheading:17675855-Retina
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pubmed:year |
2007
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pubmed:articleTitle |
Evolutionary conservation of alternative splicing in chicken.
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pubmed:affiliation |
Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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