| pubmed-article:17666805 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17666805 | lifeskim:mentions | umls-concept:C0949831 | lld:lifeskim |
| pubmed-article:17666805 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:17666805 | lifeskim:mentions | umls-concept:C0011603 | lld:lifeskim |
| pubmed-article:17666805 | lifeskim:mentions | umls-concept:C0001563 | lld:lifeskim |
| pubmed-article:17666805 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:17666805 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:17666805 | pubmed:dateCreated | 2007-8-1 | lld:pubmed |
| pubmed-article:17666805 | pubmed:abstractText | Epicutaneously administered chemical antigens like 2,4-dinitrofluorobenzene (DNFB), evoke an atopic dermatitis (AD)-like dermatitis reaction in NC/Nga mice under specific pathogen free (SPF) conditions. Astragalus membranaceus (AM), is a popular herbal medicine used to treat allergic diseases in East Asia. In the present study, we examined whether AM suppress AD-like skin lesions in NC/Nga mice treated with DNFB under SPF conditions. Oral administration of AM to DNFB-treated NC/Nga mice was found to inhibit ear thickness increases and the skin lesions induced by DNFB. Moreover, IFN-gamma production by CD4(+) T cells from the lymph nodes of DNFB-treated NC/Nga mice was significantly inhibited by AM treatment, although levels of IL-4 and total IgE in serum were not. Study findings suggest that AM may suppress the development of AD-like dermatitis in DNFB-treated NC/Nga mice by reducing IFN-gamma production. | lld:pubmed |
| pubmed-article:17666805 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17666805 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17666805 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17666805 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:17666805 | pubmed:issn | 0918-6158 | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:GeumDonghoD | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:AhnHyun-JongH... | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:ParkCheung-Se... | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:ChoJeong-JeJJ | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:SeoSang-WanSW | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:LeeSu-JinSJ | lld:pubmed |
| pubmed-article:17666805 | pubmed:author | pubmed-author:OhSeung-GeunS... | lld:pubmed |
| pubmed-article:17666805 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17666805 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:17666805 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17666805 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17666805 | pubmed:pagination | 1468-71 | lld:pubmed |
| pubmed-article:17666805 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:meshHeading | pubmed-meshheading:17666805... | lld:pubmed |
| pubmed-article:17666805 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17666805 | pubmed:articleTitle | Oral administration of Astragalus membranaceus inhibits the development of DNFB-induced dermatitis in NC/Nga mice. | lld:pubmed |
| pubmed-article:17666805 | pubmed:affiliation | Department of Microbiology (BK21), College of Medicine, Kyung Hee University, #1 Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Korea. | lld:pubmed |
| pubmed-article:17666805 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17666805 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
