Linked Life Data

17666028

Source:http://linkedlifedata.com/resource/pubmed/id/17666028

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-10-23
pubmed:abstractText
Deficits in response inhibition may be at the core of the cognitive syndrome in ADHD. Here, inhibitory control mechanisms were studied in 36 ADHD-combined type and 30 healthy children by exploring the event-related brain activity during the Stop Signal task. The influence of age, gender, and previous treatment history was evaluated. The ADHD group showed reduced N200 wave amplitudes. For successful inhibitions, the N200 reduction was greatest over right inferior frontal scalp, and only the control group showed a success-related enhancement of such right frontal N200. Source analysis identified a source of the N200 group effect in right dorsolateral prefrontal cortex. Finally, a late positive wave to failed inhibitions was selectively reduced only in treatment-naïve ADHD children, suggesting that chronic stimulants may normalize late conscious error recognition. Both effects were independent of gender and age.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0048-5772
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
936-48
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Electrophysiological correlates of response inhibition in children and adolescents with ADHD: influence of gender, age, and previous treatment history.
pubmed:affiliation
Department of Psychology, Simon Fraser University, Burnaby, BC, Canada. mliotti@sfu.ca
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural