pubmed:abstractText |
Gender dimorphism in clinical manifestation of sepsis, hemorrhage, and trauma is still under investigation. Several experimental studies have indicated a protective effect of estrogen. Nonetheless, the effect of gender on hepatic ischemia/reperfusion remains controversially discussed, and the influence of estrogen is still unclear. In the present study, we investigated whether hepatic ischemia/reperfusion (I/R) injury is gender-dependent and if hepatic microvascular reperfusion injury can be prevented by estrogen.
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pubmed:affiliation |
Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Kirrberger Strasse, 66421 Homburg/Saar, Germany. chmbur@uniklinik-saarland.de
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