|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0011155,
umls-concept:C0015127,
umls-concept:C0017337,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0026882,
umls-concept:C0034348,
umls-concept:C0162638,
umls-concept:C0242606,
umls-concept:C0442805,
umls-concept:C1314792
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2007-7-30
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|
pubmed:abstractText |
SLC3 is a Friend erythroleukemic cell line established from the Pk-1(slc) mouse, a mouse model of red blood cell type-pyruvate kinase (R-PK) deficiency. This study was aimed to elucidate the mechanisms attributing to apoptosis induced by R-PK deficiency.
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0301-472X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
35
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1190-200
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|
pubmed:meshHeading |
pubmed-meshheading:17662887-Animals,
pubmed-meshheading:17662887-Apoptosis,
pubmed-meshheading:17662887-Cell Line,
pubmed-meshheading:17662887-Cell Line, Tumor,
pubmed-meshheading:17662887-Erythrocytes,
pubmed-meshheading:17662887-Flow Cytometry,
pubmed-meshheading:17662887-Genetic Predisposition to Disease,
pubmed-meshheading:17662887-Glycolysis,
pubmed-meshheading:17662887-Leukemia, Erythroblastic, Acute,
pubmed-meshheading:17662887-Mice,
pubmed-meshheading:17662887-Mutation,
pubmed-meshheading:17662887-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17662887-Oxidative Stress,
pubmed-meshheading:17662887-Pyruvate Kinase
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Glycolytic inhibition by mutation of pyruvate kinase gene increases oxidative stress and causes apoptosis of a pyruvate kinase deficient cell line.
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|
pubmed:affiliation |
Cellular and Molecular Toxicology Division, National Institute of Health and Sciences, Tokyo, Japan.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
