Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-9-24
pubmed:abstractText
Lobular intraepithelial neoplasia (LIN) is associated with an increased risk of breast malignancy. The significance of LIN diagnosed at core needle biopsy (CNB) is unclear, although many groups recommend surgical excision to rule out lesions, which would require immediate, definitive therapy. Current management options include clinical/mammographic observation and surgical excision. The necessity of routine surgical excision remains controversial due to conflicting opinions on the biological behavior of lobular lesions, diagnostic confusion regarding histopathology, and uncertainty of their association with high-risk lesions. The purpose of this report was to review the published data regarding the incidence of high-risk lesions associated with LIN diagnosed at CNB to clarify the indications for surgical excision.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
275-80
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Lobular neoplasia diagnosed at core biopsy does not mandate surgical excision.
pubmed:affiliation
Department of Surgery, University of Wisconsin, Madison, Wisconsin 53792-7375, USA.
pubmed:publicationType
Journal Article, Review