Linked Life Data

17662300

Source:http://linkedlifedata.com/resource/pubmed/id/17662300

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-8-27
pubmed:abstractText
A chemically grafted tris(trimethylsiloxy)silyl (tris(TMS)) monolayer on a silicon oxide substrate was used as a template for creating nanoclusters of polymer brushes. Polymer brushes were synthesized by surface-initiated polymerization of 2-methacryloyloxyethyl phosphorylcholine (MPC) and tert-butyl methacrylate (t-BMA) via atom transfer radical polymerization (ATRP) from alpha-bromoester groups tethered to the residual silanol groups on the silicon surface after generating a range of tris(TMS) coverage. CuBr/bpy and CuBr/PMDETA were used as the catalytic system for PMPC and Pt-BMA synthesis, respectively. The percentage of tris(TMS) coverage significantly influenced the thickness and morphology of the polymer brushes. Protrusions representing self-aggregation of PMPC brushes in nanopores as visualized by AFM analysis evidently suggested that PMPC brushes were distributed nanoscopically on the surface. The protrusion size and surface roughness corresponded quite well with the graft density of PMPC brushes. The fact that Pt-BMA brushes grown from nanopores were almost featureless implies that self-aggregation of PMPC brushes is truly a consequence of phase incompatibility between hydrophilic PMPC brushes and hydrophobic tris(TMS). The anti-fouling characteristic of PMPC brushes, inferred from plasma protein adsorption, was subsequently varied by controlling the surface coverage ratio between PMPC brushes and tris(TMS).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-9797
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
314
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
446-59
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Polymer brushes in nanopores surrounded by silicon-supported tris(trimethylsiloxy)silyl monolayers.
pubmed:affiliation
Organic Synthesis Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand. vipavee.p@chula.ac.th
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't