| pubmed-article:17661426 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17661426 | lifeskim:mentions | umls-concept:C0030567 | lld:lifeskim |
| pubmed-article:17661426 | lifeskim:mentions | umls-concept:C0013303 | lld:lifeskim |
| pubmed-article:17661426 | lifeskim:mentions | umls-concept:C0023570 | lld:lifeskim |
| pubmed-article:17661426 | lifeskim:mentions | umls-concept:C0085415 | lld:lifeskim |
| pubmed-article:17661426 | lifeskim:mentions | umls-concept:C0574032 | lld:lifeskim |
| pubmed-article:17661426 | lifeskim:mentions | umls-concept:C0205179 | lld:lifeskim |
| pubmed-article:17661426 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:17661426 | pubmed:dateCreated | 2007-7-30 | lld:pubmed |
| pubmed-article:17661426 | pubmed:abstractText | We assessed prospectively clinical and quality of life changes in 9 patients with Parkinson's disease (PD; H&Y > or = 3) with severe motor fluctuations and dyskinesia who started continuous daily levodopa duodenal infusion through percutaneous endoscopic gastrostomy. Seven patients completed the follow-up period. Duration of "off" periods and time with disabling dyskinesia shortened significantly in all patients (P < 0.01). Total daily dose of levodopa infused did not differ from baseline equivalents. There were significant improvements in UPDRS-II (activities of daily living) and -IV (motor complications) in the "on" condition (P < 0.02), and in four PDQ-39 domains (mobility, activities of daily living, stigma, bodily discomfort; P < 0.05). Two patients withdrew for adverse events. Our results demonstrate that a satisfactory therapeutic window can be achieved and maintained for several months in advanced PD patients. | lld:pubmed |
| pubmed-article:17661426 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17661426 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17661426 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17661426 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17661426 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17661426 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17661426 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17661426 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17661426 | pubmed:issn | 0885-3185 | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:ManciniFrance... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:AntoniniAngel... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:CanesiMargher... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:PezzoliGianni... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:LopianoLeonar... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:ManfrediLuigi... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:ZibettiMauriz... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:IsaiasIoannis... | lld:pubmed |
| pubmed-article:17661426 | pubmed:author | pubmed-author:Dal... | lld:pubmed |
| pubmed-article:17661426 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17661426 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:17661426 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:17661426 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17661426 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17661426 | pubmed:pagination | 1145-9 | lld:pubmed |
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| pubmed-article:17661426 | pubmed:meshHeading | pubmed-meshheading:17661426... | lld:pubmed |
| pubmed-article:17661426 | pubmed:meshHeading | pubmed-meshheading:17661426... | lld:pubmed |
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| pubmed-article:17661426 | pubmed:meshHeading | pubmed-meshheading:17661426... | lld:pubmed |
| pubmed-article:17661426 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17661426 | pubmed:articleTitle | Duodenal levodopa infusion for advanced Parkinson's disease: 12-month treatment outcome. | lld:pubmed |
| pubmed-article:17661426 | pubmed:affiliation | Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy. angelo3000@yahoo.com | lld:pubmed |
| pubmed-article:17661426 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17661426 | pubmed:publicationType | Clinical Trial | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17661426 | lld:pubmed |
