Source:http://linkedlifedata.com/resource/pubmed/id/17661084
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2007-11-6
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pubmed:abstractText |
Intratumoral estradiol levels in postmenopausal women with breast cancer are thought to be mainly regulated by the aromatase-mediated conversion from androgens and estrogen sulfotransferase (EST)-mediated reduction of bioavailability. While in invasive breast cancer (IBC) the role of both enzymes has been extensively studied and has led to the use of aromatase inhibitors as a key therapeutic strategy, comparably little is still known about their role in the local regulation of estradiol in ductal carcinoma in situ (DCIS).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1432-1335
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-73
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pubmed:dateRevised |
2009-3-17
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pubmed:meshHeading |
pubmed-meshheading:17661084-Aromatase,
pubmed-meshheading:17661084-Breast Neoplasms,
pubmed-meshheading:17661084-Carcinoma, Ductal, Breast,
pubmed-meshheading:17661084-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:17661084-Epithelium,
pubmed-meshheading:17661084-Female,
pubmed-meshheading:17661084-Humans,
pubmed-meshheading:17661084-Immunoenzyme Techniques,
pubmed-meshheading:17661084-Middle Aged,
pubmed-meshheading:17661084-Neoplasm Staging,
pubmed-meshheading:17661084-Prognosis,
pubmed-meshheading:17661084-Stromal Cells,
pubmed-meshheading:17661084-Sulfotransferases,
pubmed-meshheading:17661084-Tissue Array Analysis
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pubmed:year |
2008
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pubmed:articleTitle |
Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Division of Special Gynecology, University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
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pubmed:publicationType |
Journal Article
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