Linked Life Data

17659614

Source:http://linkedlifedata.com/resource/pubmed/id/17659614

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-7-31
pubmed:abstractText
Conventional single-voxel localization for MR spectroscopy (MRS) is restricted to selecting only rectangular-shaped regions of interest (ROIs). The complexity of tissue shapes of interest and the desire to maximize the signal-to-noise ratio (SNR) while minimizing partial-volume effects require more sophisticated localization techniques. A group of spatially selective RF pulses are proposed in this work for the measurement of spectra from regions of arbitrary shape based on using a radial trajectory in k-space. Utilizing a single k-line per excitation results in a broad spectroscopic bandwidth. However, spatial localization accuracy is compromised for nutation angles > 10 degrees because of the small-tip-angle approximation of the Bloch equations. By interleaving multiple radial k-lines per excitation with nonselective refocusing pulses, one can achieve accurate localization for nutation angles up to 90 degrees while simultaneously maintaining the spectral bandwidth. The technique is described and compared with existing localization methods, and in vivo results are demonstrated.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0740-3194
pubmed:author
pubmed:copyrightInfo
(c) 2007 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-26
pubmed:dateRevised
2011-9-22
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
2D arbitrary shape-selective excitation summed spectroscopy (ASSESS).
pubmed:affiliation
Department of Biomedical Engineering, Yale University, New Haven, Connecticut 06520-8043, USA. qin.qin@aya.yale.edu
pubmed:publicationType
Journal Article, Comparative Study