Linked Life Data

1765826

Source:http://linkedlifedata.com/resource/pubmed/id/1765826

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pubmed-article:1765826pubmed:abstractTextConcentrations of preformed vitamin A and five individual carotenoids (alpha-carotene, beta-carotene, cryptoxanthin, lutein and lycopene) were determined in liver, kidney and lung tissue from 20 autopsies of subjects ranging in age from 4 mo to 86 y. Total carotenoid concentrations in liver tissue were always greater than in kidney or lung tissue within the same patient. Total carotenoid concentration in adult subjects was 2.5-77.1 nmol/g tissue (mean 21.0 nmol/g tissue) in liver tissue (n = 14), 0.2-12.7 nmol/g tissue (mean 3.1 nmol/g tissue) in kidney tissue (n = 13) and 0.1-8.4 nmol/g tissue (mean 1.9 nmol/g tissue) in lung tissue (n = 13). Carotenoid content in tissue samples from two infants was low, ranging from 0 to 1.0 nmol/g tissue. beta-Carotene and lycopene were almost always the predominant carotenoids found in liver, kidney and lung tissue. beta-Carotene was positively correlated (P less than 0.05) with alpha-carotene, lycopene and total carotenoids in all of the tissues examined. In addition, beta-carotene and total carotenoids from liver tissue were positively correlated with the same carotenoids in both kidney and lung tissue within each patient. Total vitamin A (free plus esterified) concentration was 8.7-1102.2 nmol/g tissue in liver (n = 17), 3.5-343.9 nmol/g tissue in kidney (n = 14) and 0.7-404.6 nmol/g tissue in lung (n = 14). Vitamin A concentrations were significantly correlated with both beta-carotene and total provitamin A carotenoid concentrations in liver tissue, but not in kidney or lung tissue.lld:pubmed
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pubmed-article:1765826pubmed:authorpubmed-author:SchmitzH HHHlld:pubmed
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pubmed-article:1765826pubmed:authorpubmed-author:WellmanR BRBlld:pubmed
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pubmed-article:1765826pubmed:pagination1613-21lld:pubmed
pubmed-article:1765826pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:1765826pubmed:articleTitleConcentrations of selected carotenoids and vitamin A in human liver, kidney and lung tissue.lld:pubmed
pubmed-article:1765826pubmed:affiliationDepartment of Food Science, University of Illinois, Urbana 61801.lld:pubmed
pubmed-article:1765826pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1765826pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:1765826pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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