Linked Life Data

17658261

Source:http://linkedlifedata.com/resource/pubmed/id/17658261

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2007-7-31
pubmed:abstractText
In recent years, a link between the transcriptional regulators of lineage-specific gene expression and progenitor proliferation control has emerged. A main exponent of this phenomenon is the CCAAT/enhancer binding protein (C/EBP) family of basic region-leucine zipper proteins. These transcription factors control the differentiation of a range of cell types, and have key roles in regulating cellular proliferation through interaction with cell cycle proteins. More recently, their position at the crossroads between proliferation and differentiation has made them strong candidate regulators of tumorigenesis, and C/EBPs have been described as both tumor promoters and tumor suppressors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1879-3088
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
318-24
pubmed:dateRevised
2008-8-15
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control.
pubmed:affiliation
EMBL Mouse Biology Unit, Monterotondo, Italy. nerlov@embl.it <nerlov@embl.it>
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't