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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2007-9-20
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pubmed:abstractText |
Colorectal carcinomas (CRC) express high levels of insulin-like growth factor-I/II (IGF-I/II) and the receptor (IGF-IR). We hypothesized that selective inhibition of IGF-IR would inhibit hepatic growth of human CRC in mice.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1068-9265
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2838-46
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17653802-Animals,
pubmed-meshheading:17653802-Antibodies, Monoclonal,
pubmed-meshheading:17653802-Antineoplastic Agents,
pubmed-meshheading:17653802-Apoptosis,
pubmed-meshheading:17653802-Blotting, Northern,
pubmed-meshheading:17653802-Cell Division,
pubmed-meshheading:17653802-Cell Survival,
pubmed-meshheading:17653802-Colorectal Neoplasms,
pubmed-meshheading:17653802-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17653802-HT29 Cells,
pubmed-meshheading:17653802-Humans,
pubmed-meshheading:17653802-In Situ Nick-End Labeling,
pubmed-meshheading:17653802-Liver Neoplasms, Experimental,
pubmed-meshheading:17653802-Male,
pubmed-meshheading:17653802-Mice,
pubmed-meshheading:17653802-Mice, Nude,
pubmed-meshheading:17653802-Neoplasm Transplantation,
pubmed-meshheading:17653802-Neovascularization, Pathologic,
pubmed-meshheading:17653802-Organoplatinum Compounds,
pubmed-meshheading:17653802-Receptor, IGF Type 1,
pubmed-meshheading:17653802-Vascular Endothelial Growth Factor A
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pubmed:year |
2007
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pubmed:articleTitle |
Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice.
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pubmed:affiliation |
Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, N.I.H., Extramural
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