Linked Life Data

17653126

Source:http://linkedlifedata.com/resource/pubmed/id/17653126

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2007-7-26
pubmed:abstractText
Substantial progress in understanding the biology of regulatory T cells and their roles in health and disease has been achieved in the past 10 years. This has led to an increasing interest in the possibility of using regulatory T cells as a biological therapy to preserve and restore tolerance to self antigens and alloantigens. Immunotherapy by the adoptive transfer of regulatory T cells may have several advantages over conventional treatments. However, several hurdles have to be overcome before such a therapy can enter clinical practice. This Review summarizes our current knowledge of regulatory T cells, illustrates the ongoing regulatory T-cell-based clinical trials, analyses the strengths and pitfalls of this new therapeutic approach, and highlights the future perspectives.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1474-1733
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
585-98
pubmed:dateRevised
2008-1-29
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.
pubmed:affiliation
San Raffaele Telethon Institute for Gene Therapy (HSR-TIGET), Via Olgettina-58, 20132 Milan, Italy. m.roncarolo@hsr.it
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't