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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-7-26
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pubmed:abstractText |
Neural retina leucine-zipper (NRL), a member of the basic motif leucine zipper family of transcription factors, is preferentially expressed in rod photoreceptors of the mammalian retina. Mutations in NRL are associated with retinopathies; many of these are suggested to change phosphorylation status and alter NRL-mediated transactivation of rhodopsin promoter. The purpose of this study was to identify potential kinases responsible for the phosphorylation of NRL and determine if such kinase-dependent phosphorylation is altered in disease-associated NRL mutations.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-10192380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-10838561,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-10864961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-10887186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-11385710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-11416124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-11477108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-11571286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-11694879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-11879142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-12074900,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-12393904,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-15163632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-15292180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-15591106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-15963504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-16505381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-17093405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-17113751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-17242361,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-1729696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-17335001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-7750577,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-8570600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-8982275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-9228012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-9390516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17653056-9873633
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1114-20
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pubmed:dateRevised |
2010-9-14
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pubmed:meshHeading |
pubmed-meshheading:17653056-Animals,
pubmed-meshheading:17653056-Animals, Newborn,
pubmed-meshheading:17653056-COS Cells,
pubmed-meshheading:17653056-Cercopithecus aethiops,
pubmed-meshheading:17653056-Enzyme Activation,
pubmed-meshheading:17653056-Enzyme Inhibitors,
pubmed-meshheading:17653056-Genes, Dominant,
pubmed-meshheading:17653056-Leucine Zippers,
pubmed-meshheading:17653056-MAP Kinase Signaling System,
pubmed-meshheading:17653056-Mice,
pubmed-meshheading:17653056-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:17653056-Mitogen-Activated Protein Kinases,
pubmed-meshheading:17653056-Mutation,
pubmed-meshheading:17653056-Phosphorylation,
pubmed-meshheading:17653056-Promoter Regions, Genetic,
pubmed-meshheading:17653056-Retina,
pubmed-meshheading:17653056-Retinal Diseases,
pubmed-meshheading:17653056-Retinitis Pigmentosa,
pubmed-meshheading:17653056-Rhodopsin,
pubmed-meshheading:17653056-Transcriptional Activation,
pubmed-meshheading:17653056-Transfection
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pubmed:year |
2007
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pubmed:articleTitle |
Mutations associated with retinopathies alter mitogen-activated protein kinase-induced phosphorylation of neural retina leucine-zipper.
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pubmed:affiliation |
Department of Cellular and Molecular Neuroscience, National Brain Research Center, Manesar, Haryana, India. prabodh@nbrc.ac.in
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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