rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2007-7-26
|
pubmed:abstractText |
Herein three cases of angle closure secondary to neovascularization (elevated intraocular pressure in two of the cases) treated with the anti-vascular endothelial growth factor (VEGF) monoclonal antibody bevacizumab (Avastin) are reported. In all three cases there was rapid resolution of neovascularization and control of intraocular pressure. One patient with corneal anaesthesia from diabetes developed infectious keratitis, potentially as a consequence of inhibition of VEGF wound healing and neurotrophic functions. Avastin appears to have a promising role in the treatment of neovascular glaucoma but is not without potential local and systemic side-effects.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1442-6404
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
494-6
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:17651259-Aged, 80 and over,
pubmed-meshheading:17651259-Angiogenesis Inhibitors,
pubmed-meshheading:17651259-Antibodies, Monoclonal,
pubmed-meshheading:17651259-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:17651259-Female,
pubmed-meshheading:17651259-Glaucoma, Neovascular,
pubmed-meshheading:17651259-Humans,
pubmed-meshheading:17651259-Injections,
pubmed-meshheading:17651259-Intraocular Pressure,
pubmed-meshheading:17651259-Iris,
pubmed-meshheading:17651259-Male,
pubmed-meshheading:17651259-Middle Aged,
pubmed-meshheading:17651259-Neovascularization, Pathologic,
pubmed-meshheading:17651259-Vascular Endothelial Growth Factor A,
pubmed-meshheading:17651259-Vitreous Body
|
pubmed:year |
2007
|
pubmed:articleTitle |
Bevacizumab (Avastin) for the treatment of neovascular glaucoma.
|
pubmed:affiliation |
Sydney Eye Hospital, and Save Sight Institute, Sydney, New South Wales, Australia.
|
pubmed:publicationType |
Journal Article,
Case Reports
|