|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005684,
umls-concept:C0024429,
umls-concept:C0026809,
umls-concept:C0026882,
umls-concept:C0312359,
umls-concept:C0332281,
umls-concept:C0456148,
umls-concept:C0580822,
umls-concept:C1334507,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594
|
|
pubmed:dateCreated |
2007-8-8
|
|
pubmed:abstractText |
Inflammatory cytokines may promote tumorigenesis. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with regulatory properties over tumor suppressor proteins involved in bladder cancer. We studied the development of bladder cancer in wild type (WT) and MIF knockout (KO) mice given N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN), a known carcinogen, to determine the role of MIF in bladder cancer initiation and progression.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-10562313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-10617637,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-10918163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-11161003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-11751895,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-11985788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-12473586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-12538581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-12878730,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-15017269,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-15248897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-15664192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-16002723,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-16449971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-16528288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-16835407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-1701519,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-17310986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-5229858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-7490328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-8804500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-9034724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17650334-9892616
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1471-2407
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
135
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:17650334-Animals,
pubmed-meshheading:17650334-Butylhydroxybutylnitrosamine,
pubmed-meshheading:17650334-Disease Progression,
pubmed-meshheading:17650334-Gene Expression,
pubmed-meshheading:17650334-Immunohistochemistry,
pubmed-meshheading:17650334-Intramolecular Oxidoreductases,
pubmed-meshheading:17650334-Macrophage Migration-Inhibitory Factors,
pubmed-meshheading:17650334-Male,
pubmed-meshheading:17650334-Mice,
pubmed-meshheading:17650334-Mice, Knockout,
pubmed-meshheading:17650334-Mutation,
pubmed-meshheading:17650334-Neoplasm Invasiveness,
pubmed-meshheading:17650334-Neoplasm Staging,
pubmed-meshheading:17650334-RNA, Messenger,
pubmed-meshheading:17650334-Urinary Bladder Neoplasms
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice.
|
|
pubmed:affiliation |
Division of Urology, University of Connecticut Health Center, Farmington, CT, USA. jtaylor@uchc.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
