Linked Life Data

17647291

Source:http://linkedlifedata.com/resource/pubmed/id/17647291

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2007-8-6
pubmed:abstractText
Oligodendrocytes (OGs) assemble the myelin sheath around axons in the central nervous system. Specification of cells into the OG lineage is largely the result of interplay between bone morphogenetic protein, sonic hedgehog and Notch signaling pathways, which regulate expression of transcription factors (TFs) dictating spatial and temporal aspects of oligodendrogenesis. Many of these TFs and others then direct OG development through to a mature myelinating OG. Here we describe signaling pathways and TFs that are inductive, inhibitory, and/or permissive to OG specification and maturation. We develop a basic transcriptional network and identify similarities and differences between regulation of oligodendrogenesis in the spinal cord and brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0894-1491
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2007 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1287-99
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Transcriptional control of oligodendrogenesis.
pubmed:affiliation
Laboratory of Molecular Biology, College of Pharmacy and Nutrition, University of Saskatchewan, and Cameco MS Neuroscience Research Center, City Hospital, Saskatoon, Saskatchewan, Canada.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't