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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7-8
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pubmed:dateCreated |
2007-10-30
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pubmed:abstractText |
The Euphorbia hirta ethanolic extract (EH A001) was found to possess a prominent anti-anaphylactic activity. A preventive effect of EH-A001 given by oral route at dose from 100 to 1000 mg/kg was observed against compound 48/80-induced systemic anaphylaxis. At the same range of dose, EH-A001 inhibited passive cutaneous anaphylaxis (PCA) in rat and active paw anaphylaxis in mice. A suppressive effect of EH-A001 was observed on the release of TNF-alpha and IL-6 from anti-DNP-HSA activated rat peritoneal mast cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0367-326X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
535-9
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pubmed:meshHeading |
pubmed-meshheading:17643865-Administration, Oral,
pubmed-meshheading:17643865-Anaphylaxis,
pubmed-meshheading:17643865-Animals,
pubmed-meshheading:17643865-Dose-Response Relationship, Drug,
pubmed-meshheading:17643865-Euphorbia,
pubmed-meshheading:17643865-Histamine H1 Antagonists,
pubmed-meshheading:17643865-Interleukin-6,
pubmed-meshheading:17643865-Mast Cells,
pubmed-meshheading:17643865-Mice,
pubmed-meshheading:17643865-Passive Cutaneous Anaphylaxis,
pubmed-meshheading:17643865-Peritoneum,
pubmed-meshheading:17643865-Phytotherapy,
pubmed-meshheading:17643865-Plant Components, Aerial,
pubmed-meshheading:17643865-Plant Extracts,
pubmed-meshheading:17643865-Rats,
pubmed-meshheading:17643865-Rats, Wistar,
pubmed-meshheading:17643865-Tumor Necrosis Factor-alpha,
pubmed-meshheading:17643865-p-Methoxy-N-methylphenethylamine
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pubmed:year |
2007
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pubmed:articleTitle |
Anti-anaphylactic effect of Euphorbia hirta.
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pubmed:affiliation |
Division of Pharmacology and Natural Product Chemistry, Indian Institute of Integrative Medicine, Jammu-Tawi, India. msyousf@rediffmail.com
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pubmed:publicationType |
Journal Article
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