Linked Life Data

17639555

Source:http://linkedlifedata.com/resource/pubmed/id/17639555

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-12-6
pubmed:abstractText
Triterpenoids, which are widely distributed throughout the plant kingdom, were applied to the development of functional foods as physiological and pharmacological active agents. Some physiological activities of a triterpenoid-rich extract from bamboo shavings (EBS), i.e. antihyperlipidemic and antihypertensive effects, were systematically evaluated in the present study. The results demonstrated that EBS could reduce the serum total cholesterol (TC) and total triglyceride (TG) levels, which are the main factors directly leading to pathological changes in cardiovascular diseases, in hyperlipidemic rats (p < 0.05). Furthermore, EBS could significantly reduce the systolic pressure of spontaneously hypertensive rats (SHR) but its maximum effect time was less than 24 h. Meanwhile, EBS did not influence the heart rate of SHR. On the other hand, the vasodilator effects of friedelin, a main triterpenoid compound separated from EBS, on phenylephrine-induced vasoconstriction in the thoracic aortas of rats were also discussed. The results showed that friedelin probably served a function of vasodilator responses in the thoracic aortas of rats in accordance with the antihypertensive effect of EBS. The results also suggested that EBS might prevent some cardiovascular diseases by its impact on lipid metabolism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0951-418X
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2007 John Wiley & Sons, Ltd.
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1135-41
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Antihyperlipidemic and antihypertensive effect of a triterpenoid-rich extract from bamboo shavings and vasodilator effect of friedelin on phenylephrine-induced vasoconstriction in thoracic aortas of rats.
pubmed:affiliation
Department of Food Science and Nutrition, School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310029, Zhejiang, PR China.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't