Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1976-6-2
|
pubmed:abstractText |
Antibody-dependent lymphocyte cytotoxicity (ADLC) was demonstrated against Epstein-Barr virus (EBV)-infected RAJI cells with peripheral with peripheral blood lymphocytes from EBV-infected donors. No cytotoxic activity was detected against unifected RAJl cells. The results indicated that this antibody-mediated cytotoxic reaction was directed against the same EBV-induced membrane antigens (MA) previously defined by the membrane immunofluorescence (MF) assay. Antibody to EBV-associated early antigens did not participate in this in vitro reaction. Antibody titers to EBV-induced MA were significantly higher by the ADLC assay in comparison with the MF test. A preliminary study showed no relationship between high antibody titers and the presence of EBV-associated malignancies. The possible in vivo significance of this immune reaction was discussed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0027-8874
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
56
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
485-8
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:176393-Antibodies, Viral,
pubmed-meshheading:176393-Antigens, Viral,
pubmed-meshheading:176393-Burkitt Lymphoma,
pubmed-meshheading:176393-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:176393-Fluorescent Antibody Technique,
pubmed-meshheading:176393-Herpesvirus 4, Human,
pubmed-meshheading:176393-Humans,
pubmed-meshheading:176393-Lymphocytes,
pubmed-meshheading:176393-Nasopharyngeal Neoplasms
|
pubmed:year |
1976
|
pubmed:articleTitle |
Antibody-dependent lymphocyte cytotoxicity against cells expressing Epstein-Barr virus antigens.
|
pubmed:publicationType |
Journal Article
|