Source:http://linkedlifedata.com/resource/pubmed/id/17639193
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2007-7-19
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pubmed:abstractText |
The purpose of this study was to evaluate the residual antibacterial activity of several calcium hydroxide [Ca(OH)2]-based pastes, placed in root canals of dogs' teeth with induced chronic periapical lesions. Root canals were instrumented with the ProFile rotary system and filled with 4 pastes: G1 (n=16): Ca(OH)2 paste + anesthetic solution; G2 (n=20): Calen paste + camphorated p-monochlorophenol (CMCP); G3 (n=18): Calen; and G4 (n=18): Ca(OH)2 paste + 2% chlorhexidine digluconate. After 21 days, the pastes were removed with size 60 K-files and placed on Petri plates with agar inoculated with Micrococcus luteus ATCC 9341. Pastes that were not placed into root canals served as control. After pre-diffusion, incubation and optimization, the inhibition zones of bacterial growth were measured and analyzed by Mann-Whitney U test at 5% significance level. All pastes showed residual antibacterial activity. The control samples had larger halos (p<0.05). The mean residual antibacterial activity halos in G1, G2, G3 and G4 were 7.6; 10.4; 17.7 and 21.4 mm, respectively. The zones of bacterial growth of G4 were significantly larger than those of G1 and G2 (p<0.05). In conclusion, regardless of the vehicle and antiseptic, all Ca(OH)2-based pastes showed different degrees of measurable residual antibacterial activity. Furthermore, unlike CMCP, chlorhexidine increased significantly the antibacterial activity of Ca(OH)2.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Hydroxide,
http://linkedlifedata.com/resource/pubmed/chemical/Camphor,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorhexidine,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorophenols,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Root Canal Filling Materials,
http://linkedlifedata.com/resource/pubmed/chemical/camphorated parachlorophenol,
http://linkedlifedata.com/resource/pubmed/chemical/chlorhexidine gluconate
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pubmed:status |
MEDLINE
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pubmed:issn |
0103-6440
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8-15
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pubmed:meshHeading |
pubmed-meshheading:17639193-Animals,
pubmed-meshheading:17639193-Anti-Bacterial Agents,
pubmed-meshheading:17639193-Calcium Hydroxide,
pubmed-meshheading:17639193-Camphor,
pubmed-meshheading:17639193-Chlorhexidine,
pubmed-meshheading:17639193-Chlorophenols,
pubmed-meshheading:17639193-Dogs,
pubmed-meshheading:17639193-Drug Combinations,
pubmed-meshheading:17639193-Periapical Diseases,
pubmed-meshheading:17639193-Root Canal Filling Materials,
pubmed-meshheading:17639193-Root Canal Therapy
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pubmed:year |
2007
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pubmed:articleTitle |
Residual antibacterial activity of chlorhexidine digluconate and camphorated p-monochlorophenol in calcium hydroxide-based root canal dressings.
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pubmed:affiliation |
Department of Dentistry, Federal University of Vales do Jequitinhonha e Mucuri, Diamantina, MG, Brazil. janirsoares@cite11.com.br
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pubmed:publicationType |
Journal Article
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