Source:http://linkedlifedata.com/resource/pubmed/id/17634329
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2007-7-19
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pubmed:abstractText |
Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1079-5006
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
794-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17634329-Absorptiometry, Photon,
pubmed-meshheading:17634329-Aged,
pubmed-meshheading:17634329-Aged, 80 and over,
pubmed-meshheading:17634329-Bone Density,
pubmed-meshheading:17634329-Female,
pubmed-meshheading:17634329-Glucuronidase,
pubmed-meshheading:17634329-Humans,
pubmed-meshheading:17634329-Longevity,
pubmed-meshheading:17634329-Male
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pubmed:year |
2007
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pubmed:articleTitle |
Bone mass of a 113-year-old man.
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pubmed:affiliation |
Hospital del Mar, Unidad de Recerca en Fisiopatología Osea i Articular, Institut d'Investigació Medica, Universidad Autónoma de Barcelona, 08003, Spain. lmellibovsky@imas.imim.es
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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