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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-7-19
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pubmed:abstractText |
The distribution of chromatin-associated proteins plays a key role in directing nuclear function. Previously, we developed an image-based method to quantify the nuclear distributions of proteins and showed that these distributions depended on the phenotype of human mammary epithelial cells. Here we describe a method that creates a hierarchical tree of the given cell phenotypes and calculates the statistical significance between them, based on the clustering analysis of nuclear protein distributions.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2121
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S3
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17634093-Breast,
pubmed-meshheading:17634093-Breast Neoplasms,
pubmed-meshheading:17634093-Cell Line,
pubmed-meshheading:17634093-Cluster Analysis,
pubmed-meshheading:17634093-Epithelial Cells,
pubmed-meshheading:17634093-Female,
pubmed-meshheading:17634093-Humans,
pubmed-meshheading:17634093-Image Processing, Computer-Assisted,
pubmed-meshheading:17634093-Imaging, Three-Dimensional,
pubmed-meshheading:17634093-Microscopy, Confocal,
pubmed-meshheading:17634093-Models, Statistical,
pubmed-meshheading:17634093-Nuclear Proteins,
pubmed-meshheading:17634093-Phenotype
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pubmed:year |
2007
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pubmed:articleTitle |
Phenotype clustering of breast epithelial cells in confocal images based on nuclear protein distribution analysis.
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pubmed:affiliation |
Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. longf@janelia.hhmi.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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