| pubmed-article:17632285 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17632285 | lifeskim:mentions | umls-concept:C0011570 | lld:lifeskim |
| pubmed-article:17632285 | lifeskim:mentions | umls-concept:C0107103 | lld:lifeskim |
| pubmed-article:17632285 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:17632285 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:17632285 | pubmed:dateCreated | 2007-7-16 | lld:pubmed |
| pubmed-article:17632285 | pubmed:abstractText | The hypothesis that brain-derived neurotrophic factor (BDNF) is involved in the pathogenesis of major depression is supported by several research findings; however, genetic studies assessing the relationship between BDNF and psychiatric disorders have produced conflicting results. We examined the effect of a BDNF polymorphism on depression susceptibility in Mexican-Americans. The single nucleotide polymorphism (Val66Met), which has been shown to have functional and behavioral effects, was genotyped in 284 depressed participants and 331 controls, showing association with depression (P=0.005). Individuals homozygous for the major allele (GG) had an increased chance of being depressed (OR=1.7 95% CI 1.17-2.47). Our findings support the association of BDNF single nucleotide polymorphism rs6265 and depression, suggesting that this polymorphism may increase susceptibility to major depression in Mexican-Americans. | lld:pubmed |
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| pubmed-article:17632285 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17632285 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17632285 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17632285 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17632285 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:17632285 | pubmed:issn | 0959-4965 | lld:pubmed |
| pubmed-article:17632285 | pubmed:author | pubmed-author:CantorRita... | lld:pubmed |
| pubmed-article:17632285 | pubmed:author | pubmed-author:RibeiroLucian... | lld:pubmed |
| pubmed-article:17632285 | pubmed:author | pubmed-author:BusnelloJoão... | lld:pubmed |
| pubmed-article:17632285 | pubmed:author | pubmed-author:WongMa-LiML | lld:pubmed |
| pubmed-article:17632285 | pubmed:author | pubmed-author:DeloukasPanos... | lld:pubmed |
| pubmed-article:17632285 | pubmed:author | pubmed-author:LicinioJulioJ | lld:pubmed |
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| pubmed-article:17632285 | pubmed:author | pubmed-author:WhelanFionaF | lld:pubmed |
| pubmed-article:17632285 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17632285 | pubmed:day | 6 | lld:pubmed |
| pubmed-article:17632285 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:17632285 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17632285 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17632285 | pubmed:pagination | 1291-3 | lld:pubmed |
| pubmed-article:17632285 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:17632285 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17632285 | pubmed:articleTitle | The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans. | lld:pubmed |
| pubmed-article:17632285 | pubmed:affiliation | Department of Psychiatry & Behavioral Sciences, Center on Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida 33136-1013, USA. lribeiro@med.miami.edu | lld:pubmed |
| pubmed-article:17632285 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17632285 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17632285 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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