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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-4-4
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pubmed:abstractText |
ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of tyrosine kinase. A previous report has suggested that overexpression of ErbB3 protein was associated with lung cancer recurrence. Other reports suggested that high ErbB3 protein expression was associated with shorter survival in advanced non-small-cell lung carcinomas (NSCLC). The relationship between the erbB3 mRNA expression and EGFR mutation has not been reported. In this study, we have investigated the erbB3 mRNA levels in reference to clinicopathologic data and EGFR mutation status in Japanese lung cancer specimens.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17631905-Adenocarcinoma,
pubmed-meshheading:17631905-Adult,
pubmed-meshheading:17631905-Aged,
pubmed-meshheading:17631905-Aged, 80 and over,
pubmed-meshheading:17631905-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:17631905-Female,
pubmed-meshheading:17631905-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:17631905-Glyceraldehyde-3-Phosphate Dehydrogenases,
pubmed-meshheading:17631905-Humans,
pubmed-meshheading:17631905-Japan,
pubmed-meshheading:17631905-Lung Neoplasms,
pubmed-meshheading:17631905-Male,
pubmed-meshheading:17631905-Middle Aged,
pubmed-meshheading:17631905-Mutation,
pubmed-meshheading:17631905-RNA, Messenger,
pubmed-meshheading:17631905-Receptor, Epidermal Growth Factor,
pubmed-meshheading:17631905-Receptor, erbB-3,
pubmed-meshheading:17631905-Sex Characteristics
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pubmed:year |
2008
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pubmed:articleTitle |
ErbB3 mRNA expression correlated with specific clinicopathologic features of Japanese lung cancers.
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pubmed:affiliation |
Department of Sugery, Nagoya City University Medical School, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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