Source:http://linkedlifedata.com/resource/pubmed/id/17629699
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
18
|
| pubmed:dateCreated |
2007-8-22
|
| pubmed:abstractText |
A series of constrained piperidine analogues were synthesized as novel muscarinic M(3) receptor antagonists. Evaluation of these compounds in binding assays revealed that they not only have high affinity for the M(3) receptor but also have high selectivity over the M(2) receptor.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0960-894X
|
| pubmed:author |
pubmed-author:AeronShellyS,
pubmed-author:ChughAnitaA,
pubmed-author:CliffeIan AIA,
pubmed-author:DharmarajanSankaranarayananS,
pubmed-author:GuptaJang BJB,
pubmed-author:GuptaSumanS,
pubmed-author:KaurKirandeepK,
pubmed-author:KumarNareshN,
pubmed-author:MehtaAnitaA,
pubmed-author:PalleVenkata PVP,
pubmed-author:SalmanMohammadM,
pubmed-author:SilamkotiArun D VAD
|
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
5256-60
|
| pubmed:meshHeading | |
| pubmed:year |
2007
|
| pubmed:articleTitle |
Synthesis and optimization of novel and selective muscarinic M(3) receptor antagonists.
|
| pubmed:affiliation |
Ranbaxy Research Laboratories, New Drug Discovery Research, Department of Medicinal Chemistry, Gurgaon, Haryana 122 001, India. n.kumar@ranbaxy.com
|
| pubmed:publicationType |
Journal Article
|