Linked Life Data

17629352

Source:http://linkedlifedata.com/resource/pubmed/id/17629352

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SubjectPredicateObjectContext
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pubmed-article:17629352pubmed:abstractTextbeta-Lactotensin (His-Ile-Arg-Leu) is an ileum-contracting tetrapeptide isolated from bovine beta-lactoglobulin. We previously reported that a neurotensin agonist beta-lactotensin shows antinociceptive effect through neurotensin NT(2) receptor. We found that centrally or orally administered beta-lactotensin at a dose of 60nmol/mouse or 300-500mg/kg, respectively, increased memory consolidation in the step-through-type inhibitory avoidance test in mice. The memory-enhancing activity of beta-lactotensin was inhibited by the dopamine D(2) receptor antagonist raclopride but not the D(1) receptor antagonist SCH23390. Taken together, beta-lactotensin might improve memory consolidation through activating the dopamine D(2) receptor.lld:pubmed
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pubmed-article:17629352pubmed:articleTitlebeta-Lactotensin, a neurotensin agonist peptide derived from bovine beta-lactoglobulin, enhances memory consolidation in mice.lld:pubmed
pubmed-article:17629352pubmed:affiliationDivision of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho Uji, Kyoto 611-0011, Japan.lld:pubmed
pubmed-article:17629352pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17629352pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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