Linked Life Data

17629352

Source:http://linkedlifedata.com/resource/pubmed/id/17629352

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2007-7-30
pubmed:abstractText
beta-Lactotensin (His-Ile-Arg-Leu) is an ileum-contracting tetrapeptide isolated from bovine beta-lactoglobulin. We previously reported that a neurotensin agonist beta-lactotensin shows antinociceptive effect through neurotensin NT(2) receptor. We found that centrally or orally administered beta-lactotensin at a dose of 60nmol/mouse or 300-500mg/kg, respectively, increased memory consolidation in the step-through-type inhibitory avoidance test in mice. The memory-enhancing activity of beta-lactotensin was inhibited by the dopamine D(2) receptor antagonist raclopride but not the D(1) receptor antagonist SCH23390. Taken together, beta-lactotensin might improve memory consolidation through activating the dopamine D(2) receptor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0196-9781
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1470-4
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
beta-Lactotensin, a neurotensin agonist peptide derived from bovine beta-lactoglobulin, enhances memory consolidation in mice.
pubmed:affiliation
Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho Uji, Kyoto 611-0011, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't