Source:http://linkedlifedata.com/resource/pubmed/id/17629283
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
16
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pubmed:dateCreated |
2007-7-26
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pubmed:abstractText |
Deceleration of the regioselective cis/trans isomerization of all-trans-astaxanthin (ASTX) in the presence of Ca2+ was shown by HPLC analysis. The NMR and ITC analyses provided evidence for complexation of ASTX with Ca2+ in 1:2 stoichiometry via chelation at both carbonyl and hydroxyl groups. The rotation across torsion omega6 (C5-C6-C7-C8) upon complexation is consistent with the NOE between 7-H and 5-CH3. This study supports the inhibitory effect of ASTX on calcium-induced turbidity of lens crystallins.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1523-7060
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2985-8
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pubmed:meshHeading |
pubmed-meshheading:17629283-Calcium,
pubmed-meshheading:17629283-Catalysis,
pubmed-meshheading:17629283-Chromatography, High Pressure Liquid,
pubmed-meshheading:17629283-Crystallins,
pubmed-meshheading:17629283-Humans,
pubmed-meshheading:17629283-Molecular Structure,
pubmed-meshheading:17629283-Stereoisomerism,
pubmed-meshheading:17629283-Thermodynamics,
pubmed-meshheading:17629283-Xanthophylls
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pubmed:year |
2007
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pubmed:articleTitle |
Properties of astaxanthin/Ca2+ complex formation in the deceleration of cis/trans isomerization.
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pubmed:affiliation |
Department of Chemistry, National Taiwan University, Taipei 106, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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