Source:http://linkedlifedata.com/resource/pubmed/id/17626882
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5835
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pubmed:dateCreated |
2007-7-13
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pubmed:abstractText |
Substances that accumulate to hazardous levels in living organisms pose environmental and human-health risks, which governments seek to reduce or eliminate. Regulatory authorities identify bioaccumulative substances as hydrophobic, fat-soluble chemicals having high octanol-water partition coefficients (K(OW))(>/=100,000). Here we show that poorly metabolizable, moderately hydrophobic substances with a K(OW) between 100 and 100,000, which do not biomagnify (that is, increase in chemical concentration in organisms with increasing trophic level) in aquatic food webs, can biomagnify to a high degree in food webs containing air-breathing animals (including humans) because of their high octanol-air partition coefficient (K(OA)) and corresponding low rate of respiratory elimination to air. These low K(OW)-high K(OA) chemicals, representing a third of organic chemicals in commercial use, constitute an unidentified class of potentially bioaccumulative substances that require regulatory assessment to prevent possible ecosystem and human-health consequences.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1095-9203
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
13
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pubmed:volume |
317
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
236-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17626882-Animals,
pubmed-meshheading:17626882-Canada,
pubmed-meshheading:17626882-Environmental Pollutants,
pubmed-meshheading:17626882-Fishes,
pubmed-meshheading:17626882-Food Chain,
pubmed-meshheading:17626882-Humans,
pubmed-meshheading:17626882-Hydrocarbons,
pubmed-meshheading:17626882-Hydrophobic and Hydrophilic Interactions,
pubmed-meshheading:17626882-Invertebrates,
pubmed-meshheading:17626882-Mammals,
pubmed-meshheading:17626882-Respiration,
pubmed-meshheading:17626882-Vertebrates
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pubmed:year |
2007
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pubmed:articleTitle |
Food web-specific biomagnification of persistent organic pollutants.
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pubmed:affiliation |
School of Resource and Environmental Management, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5A 1S6, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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