Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-2-7
pubmed:abstractText
Gastric acid output was examined following oxytocin injection into the hypothalamic paraventricular nucleus (PVN) or into the vagus nucleus (X) of the medulla in rats with insulin-hypoglycemia. Gastric acid output was reduced following the injection of nanomolar quantities of oxytocin into these nuclei, and the response was dose-dependent. It was also noted that there was a synergistic action on the response by the peptide between PVN and X. The acid response was blocked by section of the vagus nerve at the subdiaphragmatic level or by prior administration of atropine sulfate. These observations suggest that oxytocin in the PVN is active in suppressing gastric acid secretion, and the vagal response is characteristic of activation of the PVN and X.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0143-4179
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-73
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Secretion of gastric acid inhibited by oxytocin injected into the hypothalamic paraventricular nucleus in the rat.
pubmed:affiliation
Department of Surgery, Niigata University School of Medicine, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't