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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2007-7-19
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pubmed:abstractText |
Emergence of recurrent cells during androgen-deprivation therapy and intermittent androgen suppression therapy suggest that a subset of prostate cancer cells survive and proliferate in the androgen deprivation condition. Some of the recurrent cells that emerge during the androgen-deprivation therapy and intermittent androgen suppression therapy could be suppressed by replacement of androgen. In an attempt to recapitulate the clinical phenomenon, we developed an androgen-deprivation induced and androgen suppressed human prostate cancer cell line.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1293-300
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17626246-Androgen Antagonists,
pubmed-meshheading:17626246-Androgens,
pubmed-meshheading:17626246-Animals,
pubmed-meshheading:17626246-Apoptosis,
pubmed-meshheading:17626246-Cell Growth Processes,
pubmed-meshheading:17626246-Cell Line, Tumor,
pubmed-meshheading:17626246-Etoposide,
pubmed-meshheading:17626246-Humans,
pubmed-meshheading:17626246-Male,
pubmed-meshheading:17626246-Mice,
pubmed-meshheading:17626246-Mice, Nude,
pubmed-meshheading:17626246-Neoplasms, Hormone-Dependent,
pubmed-meshheading:17626246-Prostatic Neoplasms,
pubmed-meshheading:17626246-RNA, Small Interfering,
pubmed-meshheading:17626246-Receptors, Androgen,
pubmed-meshheading:17626246-STAT3 Transcription Factor
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pubmed:year |
2007
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pubmed:articleTitle |
Development of an androgen-deprivation induced and androgen suppressed human prostate cancer cell line.
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pubmed:affiliation |
Department of Medicine, Roswell Park Cancer Institute, University of Buffalo, Buffalo, NY 14263, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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